Phentermine Treatment Requires Strict Regulation

Published On April 8, 2017 | By admin | Health

Phentermine was approved as a weight loss agent by the FDA in the year 1959. Ever since the demand of it has only risen. It is a potent fat burner and appetite suppressant which together makes it desirable among those who want to shed the extra fats. Chemically, Phentermine is a substituted amphetamine and its pharmacological properties are similar to its parent compound. Due to this similarity, Phentermine medications like Adipex, Redusa, etc. are included in the schedule IV drugs by the FDA. Its sale and purchase both are regulated by the FDA and the UN convention on control substances.

Dosage indications

Phentermine is a psychostimulant drug which functions by activating certain regions in the brain. Its dosage is highly regulated in terms of the height, weight, extent of physical activity, amount of weight loss desired by the person, etc. Many reviews show that the initial dosage contains 15 mg Phentermine Hydrochloride. For exogenous obesity, the dosage is decided based on the BMI of the person and is generally higher ranging between 25 and 37 mg. However, it is only restricted to a 15mg/day in patients with renal impairment.

It is recommended that when a person develops tolerance to this drug he/she should consider discontinuing the medication. Increase in the dose or continuous dose if followed for longer periods of time may lead to addiction.

Overdosage may lead to hazardous effects

Doctors generally prescribe the lowest possible dose to a patient according to the BMI in order to avoid any chances of overdosing. Sometimes, acute overdosage might result into symptoms of restlessness, breathing problem, panic attacks or even hallucinations. It not only affects a particular region of the body but a multitude of organ systems suffer the peril if the dose is not monitored. At the cardiovascular level, one might experience arrhythmia or even circulatory collapse. While the gastrointestinal symptoms include, vomiting, abdominal cramps, nausea, etc. Studies have reported that severe over dosage of such compounds has even led to convulsions in some cases followed by coma.

Certain chronic abnormalities are linked with the abuse of Phentermine as well. Research has revealed that these patients experience vivid psychological problems and extreme dependence on the drugs which is accompanied with social oddity. Reports suggest that these patients have been using amphetamines class of drugs in much-amplified doses. The symptoms of such usage are exhibited in the forms of personality change, dermatoses, irritability, severe insomnia, etc. But the worst symptom of all is psychosis which is very similar to schizophrenia


It is the responsibility of a person to abstain from indulging in drug abuse of any kind. At the same time, it is the doctor’s duty to educate the patients about their drug of interest. Best is to prescribe a dosage that contains 15 mg Phentermine Hydrochloride, the same can be hiked if the doctor feels a requirement for it. But the patients themselves should not go against the prescription to consider increasing the dose. One should remember that phentermine is a drug prescribed for short-term treatment only and it has to be coupled with exercise, low caloric intake, and lifestyle management to fight exogenous obesity.

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